Rickets with Alopecia Signals Vitamin D Dependent Rickets Type II
نویسندگان
چکیده
منابع مشابه
Alopecia in patients with vitamin D-resistant rickets type-II*
Dear Editor, Rickets is the most common bone disease in childhood.1 The vitamin D-dependent type II (VDDR-II) is a rare and severe type of hereditary rickets described, in references worldwide, as affecting only 50 families.2 This report is designed to describe the first hereditary rickets case reported in the city of Curitiba, in which the patient displays alopecia as a frequent clinical derma...
متن کامل[Five cases of vitamin D-dependent rickets type II with alopecia].
We examined the effects of 1, 25-dihydroxyvitamin D3 on the growth and differentiation of cultured human hair follicle cells from a patient with vitamin D-dependent rickets type II [DDR-II] with alopecia. In the presence of 100 nM 1, 25-dihydroxyvitamin D3, the clonal growth of normal hair follicle cells was inhibited and terminal differentiation was markedly stimulated. However, the cells from...
متن کاملVitamin D-dependent Rickets
1,25(0H)2D3 induces 25(OH)D3-24-hydroxylase (24-OHase) in cultured skin fibroblasts from normal subjects. We evaluated 24-OHase induction by 1,25(0H)2D3 in skin fibroblasts from 10 normal subjects and from four unrelated patients with hereditary resistance to 1,25(OH)2D or vitamin D-dependent rickets type II (DD II). Fibroblasts were preincubated with varying concentrations of 1,25(0H)2D3 for 1...
متن کاملVitamin D - Dependent Rickets, Type II Case Report
AIM The aim of this work the report of one case with vitamin D-dependent rickets, type II. METHODS Diagnosis has been established based on anamnesis, physical examination, laboratory findings and radiological examination. RESULTS A female child (age 25 months) has been hospitalized due to bone deformity, bone pain, alopecia and walking difficulties. The laboratory findings have revealed tha...
متن کاملVitamin D dependent rickets type I
Vitamin D is present in two forms, ergocalciferol (vitamin D(2)) produced by plants and cholecalciferol (vitamin D(3)) produced by animal tissues or by the action of ultraviolet light on 7-dehydrocholesterol in human skin. Both forms of vitamin D are biologically inactive pro-hormones that must undergo sequential hydroxylations in the liver and the kidney before they can bind to and activate th...
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ژورنال
عنوان ژورنال: Journal of Nepal Paediatric Society
سال: 2016
ISSN: 1990-7982,1990-7974
DOI: 10.3126/jnps.v35i2.13129